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Pioneering Neurobiologist Dr. Louann Brizendine Says Women's Brains Get an "Upgrade" as They Age. Here's Why

Pioneering Neurobiologist Dr. Louann Brizendine Says Women's Brains Get an "Upgrade" as They Age. Here's Why

By Stacey Lindsay
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Neurobiologist Dr. Louann Brizendine has pioneered a new lens through which to look at the brain—one that sheds light on the cognitive differences (and similarities) between women's and men's brains. Her best-selling books The Female Brain and The Male Brain overturn stereotypes and offer ah-ha moments.

The same can be said for her latest book, The Upgrade. Geared toward the 35-plus crowd (but serviceable for younger readers), the book offers readers a look at the shifts that happen to the female brain as it ages. During menopause and beyond, a woman’s brain is “reshaped”—all for the better, Dr. Brizendine claims. “There are all kinds of things that get better after the waves of the hormones calm down. You’re able to use your brain for more focus when you get older after you get finished with the rock and roll of the fertility hormones,” she says.

A roadmap underscored by the latest scientific research, The Upgrade is a compass to reclaiming your mid-life years and beyond with enthusiasm. Curious to learn more? We spoke to Dr. Brizendine about her new book. Here are some of our favorite takeaways about what happens to the female brain as we get older from The Upgrade.

#1: We get happier.

It’s one of the “coolest” aspects of her research, exclaims Dr. Brizendine: With each decade, we actually get happier. “It’s called the positivity effect,” she says. “It’s important to know because it’s almost counterintuitive, as we tend to say and think the opposite. But each decade of your life you tend to get happier.”

#2: We get more direct.

Dr. Brizendine explains that as women age, there is a decrease in estrogen waves which changes the way the brain handles anger and disappointment. “The younger female brain diverts the impulse to stand up for ourselves and for the values that we hold,” she says. “We’re trying to impose that we’re supposed to be perfect and the people pleaser.” As we age, this biologically changes and we experience more directness. “We start to redefine the rules of relationships and speak up for what’s right,” she adds.

#3: We gain more focus.

The anxiety-provoking stress of multitasking is over, says Dr. Brizendine. “With The Upgrade, we focus on one thing at a time. We become more engaged and more thorough and better able to concentrate. We keep our eye on the prize.”

One final note: Dr. Brizendine says the greatest takeaway she wants readers to have is knowing that it does get better. That’s why caring for our minds and bodies—through all stages of life—is critical. “It’s important for us to have hope and to know that it’s worth it, to keep on persevering and doing the best you can for yourself because it matters for your brain, it matters for your happiness, it matters for the people you love in your life, and it matters for the joy you can have.”

Dr. Louann Brizendine completed her degree in Neurobiology at UC Berkeley, and she graduated from Yale School of Medicine and did her internship and residency at Harvard Medical School. She served on both the faculties of Harvard University and University of California at San Francisco. Dr. Brizendine founded the Women’s Mood and Hormone Clinic at UCSF. Her new book, The Upgrade: How the Female Brain Gets Stronger and Better in Midlife and Beyond, is out now. You can learn more here.

Stacey Lindsay

Stacey Lindsay is a journalist and Senior Editor at The Sunday Paper. A former news anchor and reporter, Stacey is passionate about covering women's issues. Learn more at:

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